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vala andishan Company

Issue raised by doctor Mohammadi poultry diseases specialist and faculty member of Vala andishan company

" prevention and treatment of mycoplasmas in poultry"

Mycoplasma is a genus of bacteria which does not have cell wall. Lack of cell wall cause it get resistant against antibiotics affecting the cell wall like penicillins. Some species of these bacteria are

saprofite or parasite and pathogenic. They do not have any flagellum or other external appendices. They need cholesterol and likely other strolls to grow

The most important problems in breeding farms:
1-    Respiratory complexes
2-    Renal lesions
Factors of respiratory complexes development
1-    Micro organisms
2-    Adverse conditions
3-    Hypersensitivity of respiratory apparatus
Different factors are involved in development of respiratory complexes in the case of adverse conditions, such as:
1-    Moisture:
Except the north of Iran, which is humidity is about 60%, other regions of Iran have low humidity, so the birds respiratory apparatus is more sensitive.
2-    Temperature:
High temperature leads to hyper breathing of the bird which causes insertion of more dust to the respiratory system.
3-    Light:
Exceed light leads to bird hyperactivity and rising more dust in the hall which causes insertion of more pathogenic particles to the bird respiratory system.
The appropriate light for the halls is 5 lux.
(lux: light which human can hardly read something in it)
4-    The quality of floor
The less moisture exist in the floor, the more dust inserts to the bird respiratory system.
5-    Ventilation:
Good ventilation helps the bird to be healthy
6-    Nutrition:
Good nutrition also is effective in the bird health. For example: less dust rises in the hall about rations containing oil
Micro organisms:
A large number of microorganisms cause respiratory problems, such as:
1-    Mycoplasmas especially galisepticum(M.G( and synoviae
2-    Viruses(infectious bronchitis, Newcastle, and even vaccine strains)
3-    E. Coli
4-    Ornithobacterium rhinotracheale
5-    Ovibacterium paragalinarum(rather in broiler and breeder herds)
Mycoplasmas are respiratory pathogens which even presence of them predispose tendency to develop disease by other pathogens.
For example, without presence of MG(Mycoplasma galisepticum) and plat, E.Coli is not able to develop respiratory infection.
If gold MG is positive, even vaccine strains(Newcastle,bronchitis, etc) cause disease.
Respiratory cilia stop function because of mycoplasma existence and any pathogen can easily rich to the depth of lungs.
Methods for identification of mycoplasma infection are:
1-    Rapid
2-    ELISA
3-    PCR
4-    Culture
Mycoplasmas are intercellular and permeate to the  cells. So, antibiotics which are more cell absorbable, have more successful action.
Treatment procedure:
Among antibiotics that are effective on mycoplasmas are: macrocides(erythromycin, tylosin, tilmycosin)
One of effective antibiotics on mycoplasmas is iveosine which is one of type 2 macrocides generation.
The most important characteristics of this product is its high permeability to cells which causes the best effect on mycoplasmas and 1 hour after drug consumption, riches to the maximum plasma concentration.
The amount of this drug consumption is:
One 25gram sachet for 14000 chickens(each one 45 grams) each day or 1/5 sachet per 1000 kg live weight, which is water soluble. This amount is better to provide in two turns( the first round at the morning and the second one after several hours). The drug should be provided daily in cold water.
Ivelosine characteristics:
1-    Prevents mycoplasma permeability to the cells because of Isovaly group.
2-    Well dissolved in water
3-    Withdrawal time is 2 days comparing with tricomycosine which has 12 days withdrawal time.
4-    It has the most permeability comparing to other antibiotics
5-    It has anti inflammatory properties and reduces lung lesions.
6-    It has synergism with tetracycline
Treatment period: 2 days and prevention period: 3 days

The next subject raised by Doctor shirin abadi Aquatic physiologist and technical director of Vala andishan company
" Washing and disinfection of poultry farms"
Clearing that include the followings:
1-    Wash
2-    Disinfection

Wash purpose:
Reduce the use or non- use of antibiotics

Wash divides to two groups:
1-    Dry wash
2-    Vet wash
Dry wash:
It is the removal of organic substances of the hall. This should carefully done especially since respiratory problems is present at the region and dust causes pathogens distribution. It is recommended to make floor slightly wet so that less dust raises.
Vet wash:
Good washing eliminates 80% of pathogens. With a good washing program, successful disinfection can be obtained.
contrary to public idea which think abundant foam causes better washing, it should be noted that, foam itself is a factor of some pathogens maintenance. A good material for washing is one can remain in walls and floor of the hall and fill inside of the grooves and cracks and can be cleaned with cold water. So, today those washing materials are used which are in gel form by the name BioGel, they have good adhesion and remove all pathogens from the surface when are washed off surfaces with cold water.
bioGel is a nonionic substance which removes all fats and proteins and soot. It should remain on surface for half an hour and then washed with cold water so that destroy 80% of pathogens.
1-    Essentially, wash the hall before disinfection of the hall and equipment, because the more is the pollution, the more disinfectant substance is needed and the costs increases.
2-    Organic materials, create a surface which decreases disinfectant to pathogen contact and so lessen the quality of disinfectant.
Disinfection, there is no natural compound for disinfection.
A good disinfectant properties:
1-    Low impact range
2-    High effective material
3-    Appropriate price and affordability.

It is a Belgian disinfectant which its inventor is a German and is a oxidant based disinfectant. It contains two effective materials including hydrogen peroxide and silver colloid that is suitable for disinfection of surfaces and equipment. 99% of this is decomposed so that 99% of pathogens are destroyed. Is usable for eliminating biofin in water pipes and even has effect in warm water upto 95. Also the amount of hydrogen peroxide is increased up-to 50% comparing with same products. Its effective materials have 3 years stability inside the product, because it is oxidative and oxidizes pathogens and finally changes to H2O and O2 and does not need washing with water.
Is usable in nebulizers at the top of birds. If the region weather is dry, it is good to intenerate the air.
CID 20:
Made in Belgium
It is the most complete disinfectant which its effective materials are:
quaternary ammonium compounds, aldehydes, alcohols and pine oil

is usable to disinfectant surfaces, walls , floor and equipment. 99% of it is decomposed and is not corrosive. After using, the hall should be washed and is not applicable in presence of the birds.
Some of its benefits are:
1-    Eliminates infection in the digestive tube
2-    Has high digestion and absorption level
3-    Keeps the bed dry
4-    Decreases FCR
5-    Increases egg-shell thickness
6-    Its taste is good for poultry



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